New grading criteria allow for earlier detection of geographic atrophy in clinical trials.
Hilary Smolen Brader, Gui-Shuang Ying, E Revell Martin...
https://pubmed.ncbi.nlm.nih.gov/22039251Completed
Phase 3
Age: 50Years +
All Genders
ID00000167
Complications of Age-Related Macular Degeneration Prevention Trial (CAPT)
Led by National Eye Institute (NEI) · Updated on 2010-03-24
1052
Participants Needed
24
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To determine whether application of low-intensity laser treatment of eyes with drusen in the macula can prevent later complications of age-related macular degeneration and thereby preserve visual function.
CONDITIONS
Brief Title
Complications of Age-Related Macular Degeneration Prevention Trial
Who Can Participate
Age: 50Years +
All Genders
Eligibility Criteria
You may qualify if you...
Patients eligible for CAPT can be either male or female and meet the following criteria:
Age at least 50 years old
Vision in each eye must measure 20/40 or better.
At least 10 large drusen in each eye
Available for follow-up examinations for 5 years after enrollment
Final eligibility is determined through a detailed eye examination by a CAPT-certified ophthalmologist.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 24 locations
1
Retinal Consultants of Arizona, Ltd.
Mesa, Arizona, United States, 85201
Status Unknown
2
Retinal Consultants of Arizona, Ltd.
Peoria, Arizona, United States, 85351
Status Unknown
3
West Coast Retina Medical Group, Inc.
San Francisco, California, United States, 94107
Status Unknown
4
University of South Florida Eye Institute
Tampa, Florida, United States, 33612-4766
Status Unknown
5
Emory Eye Center
Atlanta, Georgia, United States, 30322
Status Unknown
6
Northwestern University
Chicago, Illinois, United States, 60611
Status Unknown
7
Illinois Retina Associates, S.C.
Harvey, Illinois, United States, 60426
Status Unknown
8
University of Iowa
Iowa City, Iowa, United States, 55242-1091
Status Unknown
9
Ophthalmology & Visual Sciences at the University of Louisville, School of Medicine
Louisville, Kentucky, United States, 40202-1594
Status Unknown
10
The Johns Hopkins University
Baltimore, Maryland, United States, 21287-9223
Status Unknown
11
Ophthalmic Consultants of Boston
Boston, Massachusetts, United States, 02114
Status Unknown
12
Associate Retinal Consultants, P.C.
Royal Oak, Michigan, United States, 48073
Status Unknown
13
Mayo Clinic
Rochester, Minnesota, United States, 55905
Status Unknown
14
Barnes Retina Institute
St Louis, Missouri, United States, 63110
Status Unknown
15
Retina-Vitreous Center, P.A.
Edison, New Jersey, United States, 08820
Status Unknown
16
Retina-Vitreous Center, P.A.
Lakewood, New Jersey, United States, 08701
Status Unknown
17
Southeast Clinical Research Associates
Charlotte, North Carolina, United States, 28204
Status Unknown
18
Retina Associates of Cleveland
Cleveland, Ohio, United States, 44122
Status Unknown
19
The Ohio State University, Department of Ophthalmology
Columbus, Ohio, United States, 43210
Status Unknown
20
Casey Eye Institute
Portland, Oregon, United States, 97201-4197
Status Unknown
21
Retina Northwest, P.C.
Portland, Oregon, United States, 97210
Status Unknown
22
Scheie Eye Institute
Philadelphia, Pennsylvania, United States, 19104
Status Unknown
23
Texas Retina Associates
Dallas, Texas, United States, 75231
Status Unknown
24
University of Wisconsin - Madison, Department of Ophthalmology and Visual Sciences
Madison, Wisconsin, United States, 53705
Status Unknown
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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