Actively Recruiting

Phase Not Applicable
Age: 18Years - 89Years
All Genders
NCT05454124

Factors in Learning And Plasticity: Macular Degeneration

Led by University of Alabama at Birmingham · Updated on 2026-02-09

60

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

U

University of California, Riverside

Collaborating Sponsor

AI-Summary

What this Trial Is About

A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.

CONDITIONS

Official Title

Factors in Learning And Plasticity: Macular Degeneration

Who Can Participate

Age: 18Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18-89
  • Severely impaired vision in both eyes (20/100 or worse)
  • Diagnosis of Macular Degeneration by an Ophthalmologist
  • Light sensitivity in the macular retina at least 10 dB units worse than in peripheral regions as shown by a scanning laser ophthalmoscope (MAIA)
  • Medical records showing this disease severity has lasted at least 2 years
  • Reside within 50 miles of the study site
Not Eligible

You will not qualify if you...

  • Pacemaker or any ferromagnetic metal implanted in the body
  • Metal implants in the head (except limited dental work)
  • Claustrophobia
  • Hearing impairment
  • Weight over 300 pounds
  • Maximum body girth over 60 inches
  • Previous serious head injury
  • Presence of hallucinations or delusions
  • Extensive old or colorful tattoos, especially near the head
  • Pregnancy
  • Braces or permanent retainers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UAB

Birmingham, Alabama, United States, 35294

Actively Recruiting

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Research Team

R

Rachel A Chua, MS

CONTACT

K

Kristina M Visscher, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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