Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss: Macular Degeneration

What this Trial Is About

Researchers are studying how the brain adapts and changes after central vision loss, focusing on macular degeneration (MD), a common cause of vision loss that affects central vision. This research aims to better understand how different visual processes and brain systems work together to improve daily vision tasks such as reading, navigation, and face recognition. The study compares perceptual learning (PL) in people with natural and simulated central vision loss to explore brain plasticity and its effects on vision rehabilitation. The study evaluates two training approaches for improving vision in people with MD. One approach trains early visual processing by teaching participants to distinguish orientations of specific visual patterns (Gabor patches) at very low contrast levels. The other combines training in visual sensitivity, spatial integration, and attention to eye movements. These trainings are delivered over approximately seven weeks, with effects measured shortly after training completion. Participants will undergo assessments before and after training, including tests measuring changes in visual crowding, eye movement precision, and fixation stability. Eye-tracking and psychophysical tests will evaluate how training affects vision and brain activity. The study also involves reviewing medical records and visual sensitivity tests to confirm eligibility. Researchers will monitor participants' progress, aiming to understand how vision training can support brain plasticity and improve vision-related functions in people with MD.

Factors in Learning And Plasticity: Macular Degeneration