Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID06925308

Course of Face-to-face Interactions in Adults With Autism: An Exploratory Mixed Methods Experimental Design

Led by UMC Utrecht · Updated on 2025-04-13

54

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

Sponsors

U

UMC Utrecht

Lead Sponsor

D

Dimence Groep

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how adults with autism spectrum disorder (ASD) make eye contact during both formal and informal conversations. The study aims to understand how the type of conversation affects eye contact in terms of length, frequency, and overall behavior. It also seeks to measure physiological responses to eye contact to see if it causes increased, decreased, or unchanged stress levels, and to compare how people with ASD respond to others' eye contact versus their own. The study uses an exploratory mixed methods design with two parts. In the first part, a researcher has a conversation with an adult with ASD, including a formal and informal phase. During this conversation, hidden recordings capture the participant's eye behavior while skin conductance and eye contact measures are recorded without the participant knowing the focus on eye contact. In the second part, the participant and researcher watch the hidden recordings together while skin conductance is recorded again and specific behaviors are noted. The setup and physiological measurements are tested beforehand. Participants will be evaluated through video, audio, and skin conductance recordings to assess frequency and duration of eye contact, arousal during eye contact, and reflection on their own eye contact. The study will measure both behavioral and physiological data during interactions and review phases. The research involves adults aged 18 to 65, including neurotypical individuals and those with ASD, and participation includes interaction sessions and follow-up observation of recorded behaviors.

CONDITIONS

Brief Title

Course of Face-to-face Interactions in Adults With Autism

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged between 18 and 65 years
  • Neurotypical adults or adults diagnosed with autism spectrum disorder by an internationally recognized classification
  • Able to understand study instructions
  • Motivated to participate in research
Not Eligible

You will not qualify if you...

  • Poor command of the Dutch language
  • Use of alcohol or recreational drugs during the study
  • Mentally unstable to participate
  • Familiarity with treatment in the VGZ

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Inpatient Treatment

Duration - Single session

Participants engage in a social interaction consisting of a conversation with formal and informal phases. During this, covert recordings of eye behavior, skin conductance, and eye contact metrics are collected without the participant's awareness of the full research purpose.

1 visit (in-person)

Inpatient Treatment

Duration - Single session

Participants and researchers watch the covert recording of the participant's eye behavior. During this reflection phase, skin conductance is recorded and behavioral details are observed by the researcher.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Dimence Groep

Deventer, Overijssel, Netherlands, 7416 SB

Actively Recruiting

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Research Team

J

Jos Boer, MSc

N

Nynke Boonstra, Professor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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