Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
ID06208813

Assigned Creatine Ingestion With Usual Diet or Usual Diet Alone for Concussion Recovery

Led by San Diego State University · Updated on 2025-06-26

20

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

This research aims to compare concussion recovery between individuals who take creatine supplements and those who do not. The study focuses on measuring the number of days until participants become asymptomatic after a concussion and comparing concussion assessment scores such as symptoms, mental status, neurocognition, balance, motor coordination, and visual performance between the two groups. Participants will be randomly assigned to either a control group that consumes their usual diet without creatine or an intervention group that adds creatine supplementation to their diet. The intervention group will take 5 grams of creatine daily for the first four days after the initial meeting, then 3 grams daily thereafter until they become asymptomatic. The researchers will maintain contact with participants throughout recovery to monitor compliance and assess symptom resolution. During the study, participants will complete several assessments including the Sport Concussion Office Assessment Tool-6, computerized neurocognitive tests (CNS Vital Signs), and a visual assessment (King-Devick). These evaluations will occur at enrollment and once participants are asymptomatic. The team will analyze demographic data, days to symptom resolution, and various concussion-related measures to determine differences between groups. The study may last up to 100 weeks for each participant.

CONDITIONS

Brief Title

Creatine Supplementation in Concussion Recovery

Who Can Participate

Age: 18Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18-35 years old with a diagnosed concussion within 72 hours post-injury
Not Eligible

You will not qualify if you...

  • History of learning disability
  • History of kidney disease
  • History of mental health conditions
  • History of migraines
  • Current use of creatine or creatine use in the past 6 weeks

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - Up to 72 hours post-injury

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (in-person)

Treatment

Duration - Until asymptomatic (variable duration up to 100 weeks)

Participants will consume their usual diet with or without creatine supplementation until they become asymptomatic. The intervention group takes 5 grams of creatine daily for the first four days, then 3 grams daily thereafter until symptoms resolve. Investigators will remain in contact with participants to monitor compliance and symptom progression.

Contact frequency varies depending on recovery; typically periodic remote check-ins

Post-treatment Assessment

Duration - 1 day

Once asymptomatic, participants complete detailed concussion assessments including symptom evaluation, computerized neurocognitive tests, and a visual assessment to compare recovery outcomes.

1 assessment visit (in-person) lasting approximately 1.5 hours

Trial Site Locations

Total: 1 location

1

San Diego State University

San Diego, California, United States, 92812

Actively Recruiting

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Research Team

M

Michelle Weber Rawlins, PhD, ATC

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial