Studying Sleep Patterns and Sleep Apnea in People with Down Syndrome Including Physical Activity and Health Consequences

What this Trial Is About

Researchers are studying sleep patterns and sleep apnea in people with Down syndrome, focusing on how these sleep disorders develop and affect health. Sleep problems are common in this group, often starting in early childhood, but diagnosis can be delayed. This research aims to better understand sleep characteristics and their causes, especially sleep apnea, which involves multiple body systems. Participants include children, teenagers, and adults with Down syndrome, both with and without sleep disorders. The study observes sleep patterns over several nights and examines related factors such as physical activity, biological markers, cranial structure, and neurobehavioral issues. Assessments take place on specific days and visits, including overnight monitoring and physical activity evaluations. During the study, participants undergo sleep phenotyping over two nights and additional monitoring nights for breathing and autonomic function. Researchers collect biological samples and perform physical activity assessments to explore links with sleep-disordered breathing. The study also considers cranial structure and neurobehavioral factors. Participation lasts up to about 90 days with multiple visits for evaluations and monitoring.

Down Syndrome, Physical Activity and Sleep Apnea