Actively Recruiting
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Led by National Institute of Cardiology, Laranjeiras, Brazil · Updated on 2026-04-13
50
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.
CONDITIONS
Official Title
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of resistant hypertension confirmed in medical records
- No changes in hypertension medications or dose increases in the last 30 days
- Age between 18 and 75 years
You will not qualify if you...
- Presence of neoplasms (cancer)
- Diagnosis of heart failure
- Use of medications containing nitrate
- Patients who have undergone renal denervation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institute of Cardiology
Rio de Janeiro, Brazil, 21040-360
Actively Recruiting
Research Team
E
EDUARDO TIBIRICA, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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