Actively Recruiting
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
Led by Peking University · Updated on 2025-12-15
325
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the therapeutic effects of a digital cognitive behavioral therapy (CBT) product for treating depression through a real-world study. This study focuses on patients aged 14 to 60 years with depression, aiming to explore both the treatment impact and underlying genetic and neuroimaging mechanisms. The therapy is developed by psychotherapists to assist in managing depression and other related psychiatric or mood disorders. The treatment involves using a self-developed mobile applet that delivers digital CBT for a total of 8 weeks. Participants engage in weekly sessions that include AI-guided coursework and homework, combined with conventional drug treatment. This digital therapy is designed to be accessible through smartphones, allowing patients to participate in guided behavioral therapy remotely. During the study, participants will be assessed at weeks 4 and 8 to measure changes in depression severity using the Hamilton Depression Rating Scale (HAMD) and other related scales. Additional evaluations include anxiety, mood symptoms, sleep quality, resilience, cognitive function, side effects, and patient satisfaction. These assessments help researchers understand the therapy's effects, safety, and overall impact over the treatment period.
CONDITIONS
Brief Title
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 14 to 60 years, all genders allowed
- Hamilton Depression Rating Scale (HAMD) score of 14 or higher
- Written informed consent from the patient or guardian for minors
You will not qualify if you...
- Severe suicidal tendencies as indicated by a score of 5 or higher on item 10 of the Montgomery-Asberg Depression Rating Scale (MADRS)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants undergo digital cognitive behavioral therapy (CBT) using a mobile applet combined with conventional drug treatment. Therapy includes weekly AI-guided sessions and homework.
Weekly visits for therapy sessions
Trial Site Locations
Total: 1 location
1
Peking University Sixth Hostipal
Beijing, Beijing Municipality, China, 100191
Actively Recruiting
Research Team
W
Weihua Yue
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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