Actively Recruiting
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Led by Beijing Tiantan Hospital · Updated on 2025-02-14
120
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor. However, the mechanism is still unclear. With the development of neuroimaging, multimodal neuroimaging technology provide a new method to explore the underlying mechanism. Therefore, the purpose of this study is to analyze the alterations of brain network under sedation and anesthesia by different anesthetics in patients with supratentorial glioma and their association with cognition.
CONDITIONS
Official Title
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with unilateral supratentorial glioma by MRI
- Scheduled for selective brain tumor surgery
- Age 18 years or older
- Classified as ASA physical status I or II
- Right-handed
You will not qualify if you...
- History of cerebrovascular disease, brain trauma, chemotherapy, radiotherapy, or psychotropic drug use
- Previous intracranial surgery
- History of drug or alcohol abuse
- History of dementia or mental illness
- Pregnant or breastfeeding women
- Contraindications for MRI
- Severe bradycardia (heart rate below 40 bpm), sick sinus syndrome, or advanced heart block
- Severe liver or kidney dysfunction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tian Tan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100070
Actively Recruiting
Research Team
Y
Yuming Peng, MD,Ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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