Actively Recruiting
Effects of Bariatric Surgery on Cardiovascular Risk Profile in Relation to Inflammatory Parameters: Endothelial Phenotyping and Analysis of the Cross-talk Between Adipose Tissue and Endothelium
Led by Maria Cecilia Hospital · Updated on 2026-05-08
85
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research project aims to study how obesity affects the heart and metabolism, and how these effects change after significant weight loss following bariatric surgery. In particular, we want to look at how blood vessels and fat tissue function in people with obesity, to detect early signs of vascular problems and understand how fat tissue communicates with blood vessels. Our main idea is that obesity disrupts the normal function of blood vessels, partly due to substances released by fat tissue and changes in gut bacteria. We believe that 6 and 12 months after surgery - with proper weight loss - these problems will gradually improve. We expect to see better blood vessel function and lower levels of inflammation and fat-related substances in the blood, which could significantly reduce the overall risk of heart disease.
CONDITIONS
Official Title
Effects of Bariatric Surgery on Cardiovascular Risk Profile in Relation to Inflammatory Parameters: Endothelial Phenotyping and Analysis of the Cross-talk Between Adipose Tissue and Endothelium
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Obesity with Body Mass Index of 30 kg/m² or higher
- Scheduled for bariatric surgery via mini-gastric bypass or sleeve gastrectomy
- Able to give informed consent for personal data processing
- Willing to attend follow-up visits and complete all study assessments
You will not qualify if you...
- Active systemic inflammatory diseases such as chronic inflammatory bowel disease or chronic rheumatologic diseases
- Acute or chronic infections
- Severe anemia or coagulation disorders
- Moderate to severe chronic kidney disease
- Active malignancies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Maria Cecilia Hospital
Cotignola, Ravenna, Italy, 48033
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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