Evaluation of the Synergistic Effect of Beta-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Blood Biochemical Markers Concentrations in Trained Female Basketball Players

What this Trial Is About

Researchers are investigating the combined and separate effects of beta-alanine (BA) and sodium bicarbonate (SB) supplementation on physical performance and blood biochemical markers in highly trained female basketball players. This randomized, double-blind, placebo-controlled, parallel-group study addresses the lack of evidence about these supplements' synergistic impact, especially in female athletes, focusing on chronic supplementation and team sports performance. Participants are divided into four groups: one taking both BA and SB, one taking BA with a placebo for SB, one taking SB with a placebo for BA, and one taking placebos for both. Beta-alanine is given daily at 6.4 grams in four doses for 28 days, while sodium bicarbonate is administered from days 21 to 28 based on body weight in three doses. Placebos match the active supplements in appearance and dosing schedule to maintain blinding. Throughout the study, participants undergo tests measuring anaerobic and aerobic capacity, jump performance, and various blood markers before and after the 28-day intervention. Dietary intake, perceived exertion, heart rate, gastrointestinal symptoms, body composition, and numerous blood and urine biochemical markers are also assessed. This comprehensive monitoring helps evaluate the supplements' effects on physical capacity and biochemical status over one month.

Effects of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Biochemical Markers Concentrations