Actively Recruiting

Phase Not Applicable
Age: 20Years - 45Years
MALE
Healthy Volunteers
ID06962605

Acute Effects of Intermittent vs. Continuous Running Exercise on Physiological and Metabolic Responses

Led by National Taiwan Normal University · Updated on 2026-01-26

16

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to explore how intermittent running exercises with different interval lengths and lower intensities than high-intensity interval exercise affect energy use during and after exercise, as well as blood sugar control in healthy, recreationally active adult men aged 20 to 45. The study compares these intermittent exercises to moderate-intensity continuous running to better understand their impact on metabolic health. Participants will complete three different running trials in a random order, including moderate-intensity continuous running and two forms of interval running with 5-minute and 2-minute cycles at varied intensities. Each trial consists of a 3-minute warm-up, 40 minutes of running, and then 30 minutes of seated rest for post-exercise measurements. Trials are spaced with at least 4 days of rest and no more than 14 days apart. During the study, researchers will measure muscle oxygen levels, resting metabolic rate, total energy expenditure, substrate use, and appetite sensations across 70 minutes including exercise and recovery. Participants will be monitored for muscle oxygen saturation and metabolic changes, with procedures to minimize movement during resting periods. The entire process ensures precise tracking of physiological responses to different running exercise patterns.

CONDITIONS

Brief Title

Effects of Intermittent Running on Metabolic Health

Who Can Participate

Age: 20Years - 45Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy recreationally active men
  • BMI between 18.5-27 kg/m2
  • Aged between 20 to 45 years
  • Regular exercise at least 3 times per week for more than 3 months, including cardio exercise longer than 30 minutes at least once a week
  • Weight stable for more than 3 months (no change in weight +/- 3%)
  • Non-shift workers with 6.5-9 hours of sleep per night for the past 3 months
  • Non-smoker
Not Eligible

You will not qualify if you...

  • Having any cardiovascular, metabolic, or pulmonary disease such as angina pectoris or uncontrolled arrhythmias
  • Suffering from infectious contagious diseases
  • Using medications that affect metabolic responses, including anti-inflammatory drugs
  • Smoking
  • Heavy alcohol intake (more than 4 drinks on any day or more than 14 drinks a week)
  • Following special diets such as intermittent fasting or ketogenic diets

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - Up to 4 weeks

Participants perform three different 40-minute running exercise trials in a randomized crossover design, each separated by at least 4 days of rest.

3 visits (in-person), each including baseline measurements, 40 minutes of running exercise, and 30 minutes of post-exercise monitoring

Trial Site Locations

Total: 1 location

1

National Taiwan Normal University

Taipei, Taiwan

Actively Recruiting

Loading map...

Research Team

Y

Yung-Chih Chen, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

Similar Trials

Bath MyoRhythms Project: Characterising Rhythmicity in Human...

Metabolic Regulation

Actively Recruiting

1 location

Effect of Resistance Exercise on Energy Balance and Appetite...

Energy Balance

Actively Recruiting

1 location

Atrial Natriuretic Peptide and Regulation of Cardiometabolic...

Cardiovascular Diseases

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here