Actively Recruiting
The Effect of Menstrual Cycle Phase on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
Led by Konya City Hospital · Updated on 2026-04-21
110
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study focuses on women undergoing elective laparoscopic gynecologic surgery to evaluate how different phases of the menstrual cycle affect the optic nerve sheath diameter (ONSD). The research aims to understand if hormonal changes during the follicular or luteal phases influence intracranial pressure as reflected by ONSD measurements, and how these variations relate to postoperative nausea, vomiting, and cognitive function. Participants will be grouped based on their menstrual cycle phase: follicular phase (around days 12-14) or luteal phase (around days 20-25). During surgery, ONSD will be measured before anesthesia, during the operation, and at the end. Postoperative assessments will include monitoring nausea, vomiting, and cognitive function within 24 hours after surgery. Women in the study will undergo perioperative ONSD measurements and evaluations of postoperative symptoms and cognitive status. Researchers will measure ONSD at specific surgical time points and assess nausea, vomiting, and cognitive function before and after surgery. The full participation period includes the surgical procedure and a 24-hour postoperative follow-up to monitor these outcomes.
CONDITIONS
Brief Title
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18 to 45 years
- Scheduled for elective laparoscopic gynecologic surgery
- Menstrual cycle in the follicular phase or luteal phase
- American Society of Anesthesiologists (ASA) physical status I-II
You will not qualify if you...
- Irregular menstrual cycle such as polycystic ovary syndrome, early menopause, or hypothalamic amenorrhea
- Pregnancy or breastfeeding
- Neurological diseases affecting intracranial pressure
- Glaucoma or other eye diseases linked to high intraocular pressure
- Previous brain surgery
- Uncontrolled hypertension or severe cardiovascular disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Surgery day
Participants undergo elective laparoscopic gynecologic surgery during either the follicular or luteal phase of their menstrual cycle. Optic nerve sheath diameter measurements are taken before induction of anesthesia, during surgery, and at the end of surgery.
1 visit (in-person)
Duration - 24 hours after surgery
Participants are assessed for postoperative nausea, vomiting, and cognitive function within 24 hours after surgery.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Konya City Hospital
Konya, Turkey (Türkiye)
Actively Recruiting
Research Team
M
MAHMUT TUTAR, MD
M
MAHMUT TUTAR, md
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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