Actively Recruiting
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
Led by Elazıg Fethi Sekin Sehir Hastanesi · Updated on 2026-04-22
90
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL). Systemic inflammatory indices derived from routine complete blood count parameters, including Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), Aggregate Index of Systemic Inflammation (AISI), Neutrophil-to-Lymphocyte Ratio (NLR), and Red Cell Distribution Width (RDW), will be evaluated. Preoperative and postoperative laboratory values will be analyzed to determine whether the type of anesthesia influences systemic inflammatory markers and related clinical outcomes.
CONDITIONS
Official Title
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
Who Can Participate
Eligibility Criteria
You may qualify if you...
- American Society of Anesthesiologists (ASA) physical status class I-III
- Patients aged 18 years and older
You will not qualify if you...
- American Society of Anesthesiologists (ASA) physical status class IV or V
- Patients younger than 18 years
- Active infection or diagnosis of sepsis
- Malignancy
- Chronic inflammatory diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus)
- Use of immunosuppressive therapy
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fethi Sekin City Hospital
Elâzığ, Elaziğ, Turkey (Türkiye)
Actively Recruiting
Research Team
S
Sevim ŞENOL KARATAŞ, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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