Actively Recruiting

Age: 18Years - 65Years
All Genders
ID07288099

Prospective Observational Cohort Study Comparing Recovery Profiles After Target-Controlled Infusion Versus Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery

Led by Istanbul University - Cerrahpasa · Updated on 2026-03-24

100

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting a prospective observational study to compare recovery after video-assisted thoracoscopic surgery (VATS) using two common anesthesia methods: target-controlled infusion (TCI) and inhalational anesthesia. The study aims to observe how these anesthesia techniques, used routinely by anesthesiologists, may affect patient recovery without altering usual care practices. Patients undergoing VATS will receive anesthesia based on clinical routine, either with TCI-based total intravenous anesthesia or inhalational agents like sevoflurane. No additional interventions or randomization will be done. The study will follow patients who receive either method and collect data including demographic information, intraoperative details, drug dosing, and oxygenation. During and after surgery, researchers will track awakening time, extubation time, Aldrete score progression, sedation levels, pain scores, and early postoperative complications such as nausea and vomiting. All assessments will be based on routine clinical monitoring in the post-anesthesia care unit and surgical ward. The goal is to better understand recovery patterns linked to these anesthesia techniques over the study period ending in July 2026.

CONDITIONS

Brief Title

Target-Controlled Infusion (TCI) vs Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS)

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years
  • Scheduled for elective video-assisted thoracoscopic surgery (VATS)
  • ASA physical status I to III
  • Able to provide informed consent
  • Planned postoperative recovery in post-anesthesia care unit and surgical ward
Not Eligible

You will not qualify if you...

  • ASA physical status IV or higher
  • Hemodynamic or respiratory instability before surgery
  • Known allergy or contraindication to commonly used anesthetic agents
  • Neurological or psychiatric conditions interfering with recovery assessment
  • Emergency surgeries
  • Patients who decline participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Observational Monitoring

Duration - Day of surgery and up to 1 hour postoperatively

Participants who undergo routine anesthesia during video-assisted thoracoscopic surgery (VATS) are observed. Data on anesthesia type, intraoperative variables, and postoperative recovery including awakening, extubation times, Aldrete scores, pain scores, and early complications are collected as part of routine care.

1 surgical visit and up to 1 hour of post-anesthesia care unit monitoring

Trial Site Locations

Total: 1 location

1

Istanbul University Cerrahpasa Medical Faculty

Istanbul, Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

M

mert katılmış, md

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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