Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
ID04635436

Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication

Led by Istituto Auxologico Italiano · Updated on 2024-10-08

20

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to study dynamic asymmetries in the lower limbs of adults with unilateral motor impairments caused by conditions like post-stroke hemiparesis, Parkinson's disease, multiple sclerosis, unilateral amputation, or orthopedic surgeries. It evaluates how walking on a split-belt treadmill, where each leg moves at a different speed, affects gait patterns and neural control of walking. The study seeks to clarify the potential of this split gait as a rehabilitation tool by investigating spatial and dynamic asymmetries and their effects on body movement. Participants will perform walking tests on a split-belt treadmill with belts moving at different speeds in a specific sequence: a baseline phase with increasing speed, a short habituation phase, an adaptation phase where one leg walks faster than the other for six minutes, and a post-adaptation phase where belt speeds are equal again for six minutes. After one week, participants repeat the protocol with the affected limb on the faster belt. The treadmill is equipped with force sensors, and participants walk freely without support. During the study, researchers will assess ankle joint power, step length, single and double stance times, and center of mass motion through two assessments spaced a week apart. Participants will be informed verbally before belt speed changes. The study involves adults aged 18 to 70 who can walk at least 20 meters unaided and understand instructions. The total participation includes multiple walking sessions and repeated assessments to monitor gait adaptation and symmetry changes.

CONDITIONS

Brief Title

Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 70 years old
  • Ability to walk at least 20 meters without support
  • Ability to willingly sign informed consent
  • Ability to understand instructions and complete the walking task
  • Visual acuity better than 10/20 in the worse eye with correction
  • Unilateral motor impairment of one lower limb due to conditions like post-stroke hemiparesis, Parkinson's disease with asymmetry, multiple sclerosis with asymmetry, unilateral amputation with prosthetic, surgical orthopedic interventions, or peripheral nerve lesions
Not Eligible

You will not qualify if you...

  • Presence of systemic neurological diseases
  • Orthopedic surgeries other than those causing eligibility
  • Symptomatic spine (rachis) pathologies
  • Other sensory or neurological conditions affecting balance and walking
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Two assessments spaced one week apart

Participants perform split-belt treadmill walking tests to assess dynamic asymmetries. The test involves multiple walking phases including baseline, habituation, adaptation, and post-adaptation phases with different belt speeds.

2 visits (in-person) spaced one week apart

Trial Site Locations

Total: 1 location

1

Istituto Auxologico Italiano

Milan, MI, Italy, 20121

Actively Recruiting

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Research Team

L

Luigi Tesio, MD, Full Professor

S

Stefano Scarano, MD, Research Fellow

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Published Research Related To This Trial

Changes in lower limb muscle activity after walking on a split-belt treadmill in individuals post-stroke.

Martina Betschart, Séléna Lauzière, Carole Miéville...

https://pubmed.ncbi.nlm.nih.gov/28086163

Repeated split-belt treadmill walking improved gait ability in individuals with chronic stroke: A pilot study.

Martina Betschart, Bradford J McFadyen, Sylvie Nadeau

https://pubmed.ncbi.nlm.nih.gov/28901824

Plantarflexion moment is a contributor to step length after-effect following walking on a split-belt treadmill in individuals with stroke and healthy individuals.

Séléna Lauzière, Carole Miéville, Martina Betschart...

https://pubmed.ncbi.nlm.nih.gov/25074249