Follow-Up Study of Extremely Low Birth-Weight Infants Neurodevelopmental and Functional Assessments at 18 to 26 Months Corrected Age

What this Trial Is About

This research evaluates neurodevelopment in surviving extremely low birth-weight infants born at participating centers. The study aims to identify maternal and neonatal risk factors that may influence infant development by assessing motor skills, cognitive abilities, language, behavior, and the use of special support services. It also examines growth, socioeconomic status, mortality, and medical conditions in this high-risk infant population. Participants undergo detailed neurodevelopmental, neurosensory, and functional assessments at 22 to 26 months corrected age. The evaluations include demographic and socioeconomic data, medical history, medication use, growth measurements, neurological exams, and standardized developmental tests such as the Bayley Scales of Infant Development and the Child Behavior Checklist. A reference group of healthy term infants is also assessed to provide comparison data and ensure consistency in scoring. Throughout the study, data is collected prospectively to maintain a registry of baseline and outcome information for very low birth-weight infants. Researchers monitor developmental outcomes and related factors longitudinally to support future research and hypothesis generation. Participation involves scheduled evaluations and standardized assessments conducted at specified corrected ages, with the study continuing through March 2030.

Follow-up Visit of High Risk Infants