Study of Genetic Traits in Adults with Idiopathic Pulmonary Fibrosis to Understand Lung Scarring Patterns

What this Trial Is About

Researchers are studying idiopathic pulmonary fibrosis IPF, a lung disease that causes scarring and damage in the lungs, leading to breathing difficulties and respiratory failure. The study aims to find specific genetic traits that might explain why some patients develop pulmonary fibrosis and why the patterns of inflammation and scarring vary among them. This research focuses on understanding how genetic differences may influence the diseases progression and response to treatment. This study is observational and involves collecting genetic samples from adult patients diagnosed with pulmonary fibrosis. Participants will be evaluated based on their genetic polymorphisms in genes related to inflammation, tissue remodeling, and cell growth in the lungs. Sample collection may continue for up to five years to gather sufficient data. There are no investigational treatments being administered instead, the study monitors natural disease progression and genetic factors. Participants will undergo assessments including physical exams, lung function tests, chest X-rays, and CT scans to confirm diagnosis and monitor disease status. Genetic samples are collected to analyze variations that might affect lung repair and fibrosis development. The main outcome is the identification and correlation of genetic polymorphisms with disease patterns. The study may last several years, with ongoing sample collection and follow-up to better understand IPF.

Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)