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Actively Recruiting

Phase Not Applicable
Age: 30Years - 50Years
All Genders
ID07447011

Glaucoma Response to Lifestyle Corrections in Patients with Obstructive Sleep Apnea and Obesity

Led by Cairo University · Updated on 2026-03-03

40

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating the response of glaucoma in patients who also have obstructive sleep apnea OSA and obesity. This study focuses on patients with high-tension primary open-angle glaucoma, intraocular pressure higher than 21 mmHg, and OSA. The goal is to assess how lifestyle corrections alongside continuous positive airway pressure CPAP treatment affect glaucoma over a period of three months. The study involves 40 participants divided into two groups of 20. Both groups will use CPAP every night during sleep for three months. Group I will also follow lifestyle changes including a low-calorie diet and treadmill walking for 40 minutes, three times per week during this period. Group II will receive CPAP treatment only, without lifestyle corrections. Participants will be monitored through various measures after 12 weeks, including intraocular pressure, apnea hypopnea index, daytime sleepiness via the Epworth sleepiness scale, body mass index, waist and neck circumference, and glaucoma-related quality of life. These assessments will help researchers understand the impact of lifestyle changes combined with CPAP on glaucoma and OSA. The total study duration for each participant is three months.

CONDITIONS

Brief Title

Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea

Who Can Participate

Age: 30Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with obstructive sleep apnea
  • Patients who are obese
  • Patients diagnosed with primary open-angle glaucoma with ocular hypertension
Not Eligible

You will not qualify if you...

  • Patients with heart disease
  • Patients with kidney disease
  • Patients with liver disease

Research Team

A

Ali MA Ismail, lecturer

A

ali mohamed, lecturer

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