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ID05470023

Study to Improve Oral Health Using Imaging and Different Toothpastes or Mouthwashes in Adults

Led by University of California, Irvine · Updated on 2025-12-23

275

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

This research aims to develop improved methods for measuring oral health by using photographs and imaging software. The study evaluates the effects of different over-the-counter toothpastes and mouthwashes on oral health, focusing on plaque levels, gum health, and saliva production. The goal is to find better ways to assess mouth health and determine if specific products can improve gum condition. Participants will be randomly assigned to use one of several toothpastes or mouthrinses. Toothpaste users will brush twice daily with a provided standard toothbrush and a specific dental gel, following a trained brushing technique. Mouthrinse users will continue their usual oral hygiene and rinse twice daily with a mouthwash after brushing. Study durations vary from 7 days to 6 months, with the initial period for developing imaging techniques and longer periods to validate them. During study visits, participants will have clinical assessments including plaque, gum inflammation, and bleeding recorded, as well as saliva production measured by expectorating into a cylinder. Photos of the mouth will be taken using an intraoral camera that does not capture the face. Visits last about 30 minutes, and the same investigator will evaluate participants at each visit. The study carefully avoids professional dental cleaning to maintain consistent data.

CONDITIONS

Brief Title

Imaging-based Assessment of Oral Biofilm and Gingival Health

Research Team

D

Dr. Petra Wilder-Smith

N

Nicole Wakida, PhD

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