Actively Recruiting
Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues
Led by University of Pisa · Updated on 2026-04-01
40
Participants Needed
2
Research Sites
221 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis. Clinically, localized signs of inflammation limited to the gingiva, presence of significant bacterial plaque load, and stable attachment levels on the periodontium can be observed in course of gingivitis. The aim of the present study is to compare clinical aspects of gingival tissue in healthy patients versus patients with gingivitis to assess the ultrastructural variations present in course of inflammation. Patients with gingivitis and healthy controls will be enrolled. All patients will undergo ultra-high frequency ultrasonographic scans (70 MHz) of gingival tissue on three areas per dental arch (anterior, middle right, middle left). Gingival thickness, echogenicity, and vascularization assessed through resisitive index will be evaluated.
CONDITIONS
Official Title
Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males or females older than 18 years
- Presence of at least 20 teeth
- Full-mouth plaque score (FMPS) greater than 50%
- Full-mouth bleeding score (FMBS) greater than 30%
- Ability and willingness to give informed consent
You will not qualify if you...
- Pregnancy or breastfeeding
- Use of anti-inflammatory drugs, statins, or local or systemic antibiotics within the past 30 days
- Current smoking habit
- Dental or periodontal condition requiring immediate treatment
- Refusal to be enrolled in the study
AI-Screening
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Trial Site Locations
Total: 2 locations
1
University of Pisa
Pisa, Italy, Italy, 56126
Actively Recruiting
2
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University Hospital of Pisa
Pisa, Italy
Actively Recruiting
Research Team
R
Rossana Izzetti
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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