Effect of Propolis mouthwash on plaque and gingival indices over fixed orthodontic patients.
Mahboobe Dehghani, Mostafa Abtahi, Nadia Hasanzadeh...
https://pubmed.ncbi.nlm.nih.gov/31001394Actively Recruiting
Phase Not Applicable
Age: 13Years - 40Years
All Genders
Healthy Volunteers
ID07119840
Comparison of Clinical Effects of Listerine and Chlorhexidine Mouthwash in Patients Undergoing Fixed Orthodontic Treatment
Led by Khyber Medical University Peshawar · Updated on 2025-11-26
60
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
Sponsors
K
Khyber Medical University Peshawar
Lead Sponsor
S
Saidu College of Dentistry
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of Listerine and Chlorhexidine mouthwashes in improving gum and plaque health for patients undergoing fixed orthodontic treatment. This trial focuses on patients aged 13 to 40 years with permanent teeth who are receiving braces, as fixed appliances can cause plaque buildup leading to gum inflammation. The purpose is to compare these two mouthwashes to see which better supports periodontal health during orthodontic care. Participants will be randomly assigned to one of two groups. One group will use Listerine mouthwash containing essential oils, and the other will use Chlorhexidine mouthwash at 0.12% concentration. Both groups will rinse once daily with 10 ml of mouthwash for 30 seconds after brushing, over a 4-week period. The mouthwashes are given in unlabelled bottles to keep the study double-blind. Standard oral hygiene instructions are also provided. During the study, gum health and plaque levels will be assessed at the start, after 2 weeks, and after 4 weeks using Gingival Index and Plaque Index measurements. Side effects will be monitored throughout the 8 weeks. Oral examinations will be done by trained examiners using standard tools. Data analysis will compare the mouthwashes' effects, considering factors like age and gender. The total participation time includes baseline and follow-up assessments over 8 weeks.
CONDITIONS
Brief Title
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
Who Can Participate
Age: 13Years - 40Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Aged 13-40 years
- Have permanent teeth including first molars
- Willing to undergo fixed orthodontic treatment and follow instructions
You will not qualify if you...
- Have systemic illness such as diabetes, heart disease, or hepatitis
- Pregnant or lactating females
- Use tobacco products
- History of allergies to mouthwash or toothpaste
- Used mouthwash in the past 3 months
- Have abnormal oral morphology or parafunctional habits such as teeth grinding or clenching
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 4 weeks
Participants will use either Listerine or Chlorhexidine mouthwash once daily for 4 weeks as part of their fixed orthodontic treatment to improve periodontal health.
3 visits (baseline, 2 weeks, and 4 weeks)
Follow-up
Duration - Up to 4 additional weeks after treatment ends
Participants will be monitored for side effects and periodontal health up to 8 weeks after starting treatment.
1 visit at 8 weeks
Trial Site Locations
Total: 1 location
1
Saidu College of Dentistry
Swāt, KPK, Pakistan
Actively Recruiting
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Research Team
F
Fazli Rabi, MPH*
D
Dr Naveed Sadiq, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
The effect of fluoride varnish and chlorhexidine gel on white spots and gingival and plaque indices in fixed orthodontic patients: A placebo-controlled study.
Shiva Alavi, Navid Yaraghi
https://pubmed.ncbi.nlm.nih.gov/30123305Efficacy of chlorhexidine and green tea mouthwashes in the management of dental plaque-induced gingivitis: A comparative clinical study.
B Meena Priya, V Anitha, M Shanmugam...
https://pubmed.ncbi.nlm.nih.gov/26681856Comparison of the anti-plaque and anti-gingivitis efficacy of Chlorhexidine and Malva mouthwashes: Randomized crossover clinical trial.
Giovanna Sacco Zuttion, Humberto Alexander Baca Juárez, Betina Dutra Lima...
https://pubmed.ncbi.nlm.nih.gov/39173823Oral hygiene status among orthodontic patients.
Farhad Atassi, Fatin Awartani
https://pubmed.ncbi.nlm.nih.gov/20953561