Study of Splanchnic Vein Thrombosis in Adults with Acute Pancreatitis and its Link to Disease Severity

What this Trial Is About

This research investigates acute pancreatitis AP, an inflammation of the pancreas that affects many people and can lead to serious complications. About one-third of patients with AP develop local or systemic problems such as fluid collections, necrosis, pseudocysts, and walled-off necrosis. A significant concern in this condition is splanchnic vein thrombosis, which includes blood clots in the splenic, portal, and superior mesenteric veins. These clots are often found during imaging tests and can cause severe complications like bowel ischemia, liver failure, portal hypertension, and bleeding, especially as pancreatitis severity increases. The study is observational and aims to understand the occurrence of splanchnic vein thrombosis in acute pancreatitis and its relationship with disease severity. It also addresses the lack of standard guidelines for starting anticoagulation treatment in such patients, considering the risk of bleeding complications. Researchers will explore risk factors, causes, treatment impacts, and predictors of outcomes related to these blood clots in AP. Participants will be monitored over a period of up to one year, with assessments including imaging and clinical evaluations to detect vascular complications and their progression. The study will track primary and secondary outcomes at intervals of six months and one year to better understand the effects and risks associated with splanchnic vein thrombosis in acute pancreatitis. This information aims to improve future management and treatment recommendations.

Incidence of Splanchnic Venous Thrombosis in Acute Pancreatitis and it's Correlation With Severity of Pancreatitis