Actively Recruiting

Age: 18Years - 85Years
All Genders
NCT05777889

Infrared Images for Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients

Led by Hospital for Special Surgery, New York · Updated on 2025-11-26

12

Participants Needed

1

Research Sites

205 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to compare thermal camera Forward Looking InfraRed (FLIR) images before and after spinal cord stimulation to evaluate the difference in sympathetic activity of the affected limb in patients with complex regional pain syndrome (CRPS). The main questions it aims to answer are: Question 1: Can Infrared (FLIR) imaging be used to monitor the sympatholytic activity caused by Spinal Cord Stimulation (SCS) in patients with CRPS? Question 2: Is there any correlation between the quantification of sympatholytic activity produced by Spinal Cord Stimulation (SCS) and measured by FLIR imaging with the outcome measures in patients with CRPS? Outcome measures include pain (NRS), CRPS Severity Score (CSS), and neuropathic pain score (painDETECT). Participants will have an image of their feet taken perpendicularly with a 1-inch space from all four sides using a FLIR T420 or T62101 camera with 320\*240 resolution. Participants will also complete questionnaires about the average pain, CRPS severity, and neuropathic pain.

CONDITIONS

Official Title

Infrared Images for Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • The patient is between 18 and 85 years old
  • Diagnosed with CRPS using the Budapest Clinical Diagnostic Criteria
  • CRPS affecting one lower leg
  • Pain and symptoms lasting more than 3 months
  • Not responding to standard medical treatments and multidisciplinary care
  • High pain level of 6 or more on the NRS scale despite treatment
  • Pain limits the patient's ability to function despite appropriate treatment
Not Eligible

You will not qualify if you...

  • Suspected disc herniation, spinal stenosis, myelopathy, or radiculopathy based on MRI or CT exams
  • Systemic or local infection
  • Coagulation disorders
  • Allergy to contrast material
  • Malignancy
  • Pregnancy
  • Uncontrollable medical or psychiatric conditions
  • Diagnosed with other sympathetic or sweating disorders besides CRPS (e.g., Raynaud disease, Buerger disease, acquired idiopathic generalized anhidrosis)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital for Special Surgery

New York, New York, United States, 10021

Actively Recruiting

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Research Team

P

Pa Thor, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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