Actively Recruiting
Role of the Gut Microbiome in Complex Regional Pain Syndrome
Led by Washington University School of Medicine · Updated on 2025-11-05
140
Participants Needed
1
Research Sites
445 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this prospective, observational study is to determine the association between the composition of the gut microbiota and the severity and persistence of Complex Regional Pain Syndrome symptoms (Study A). The objective of Study B, a longitudinal study of microbiota biomarkers of patients with newly diagnosed CRPS is to determine if the researchers can predict which patients are more likely to recover compared to those who do not. A secondary objective of both studies is to examine cognitive flexibility in relation to outcomes (study A and B).
CONDITIONS
Official Title
Role of the Gut Microbiome in Complex Regional Pain Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults over the age of 18
- Current (< 1 year duration) or former (> 1 year) diagnosis of Complex Regional Pain Syndrome by the Budapest criteria (Study A cases)
- English as primary language
- Able to consent
- Adults over age of 18 who live with a person with current or former diagnosis of CRPS (Study A controls)
- Adults over the age of 18
- Recent diagnosis (<6 months) of Complex Regional Pain Syndrome by the Budapest criteria (Study B cases)
- Adults over age of 18 who live with a person diagnosed with CRPS (Study B controls)
You will not qualify if you...
- Unwilling to participate in the study
- Lives alone
- Current use of probiotics and unwilling to stop for 1 week prior to stool sample
- Pregnant or lactating
- Vegan diet
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
L
Lara Crock, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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