Actively Recruiting
Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study
Led by University Hospital, Rouen · Updated on 2026-02-17
180
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the prognostic value of the chair lift test for assessing the severity of non-severe pulmonary embolism in hospitalized patients. This study compares the chair lift test results with the current pulmonary embolism risk score called sPESI, which is enhanced by cardiac biomarkers and measures of right ventricular dysfunction. The goal is to see how well the chair lift test predicts patient outcomes compared to established methods. Participants will perform the chair lift test, which involves repeated sit-to-stand movements at a comfortable pace for one minute. This test is being studied as an experimental method to evaluate pulmonary embolism severity. The primary measure is how sensitive and specific the chair lift test is, compared to the gold standard that includes biomarkers and heart function assessments. Secondary measures include troponin levels, presence of breathing difficulties six months later, and overall survival at six months. During the study, participants will undergo the chair lift test and have troponin measured within one day. They will be followed for six months to monitor symptoms and survival. Researchers will collect data on breathing problems after pulmonary embolism and overall health outcomes. The total study period extends through these assessments to understand the test's prognostic performance and its potential clinical use.
CONDITIONS
Brief Title
Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of pulmonary embolism confirmed by thoracic angioscan or ventilation perfusion scan
- Non-serious pulmonary embolism not requiring intensive care or thrombectomy/fibrinolysis
- sPESI score 61; 1 or sPESI = 0 with elevated troponin or right ventricular dysfunction markers, or sPESI = 0 with hospitalization due to unrelated comorbidities
- No contraindications to chair lift testing (no oxygen therapy at testing)
- Effective anticoagulation for at least 1 hour
You will not qualify if you...
- sPESI score = 0 with outpatient referral
- Pulmonary embolism diagnosis confirmed more than 24 hours after suspicion
- Hospitalization more than 24 hours after starting anticoagulation with diagnosis confirmation
- Serious pulmonary embolism requiring intensive care
- Asymptomatic pulmonary embolism discovered incidentally
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete the one-minute chair lift test along with cardiac biomarker measurements and right ventricular function assessment to evaluate pulmonary embolism prognosis.
1 visit (in-person)
Duration - 6 months
Participants are followed up to assess post-pulmonary embolism symptoms and overall survival.
Follow-up assessments at 6 months
Trial Site Locations
Total: 1 location
1
Chu Rouen
Rouen, France, 76031
Actively Recruiting
Research Team
D
Delphine SIMON, MD
A
Armelle GUIDOTTI
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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