Actively Recruiting
Investigation of Subclinical Markers of Multiple Sclerosis
Led by University of Split, School of Medicine · Updated on 2023-10-02
50
Participants Needed
1
Research Sites
422 weeks
Total Duration
On this page
Sponsors
U
University of Split, School of Medicine
Lead Sponsor
U
University Hospital of Split
Collaborating Sponsor
AI-Summary
What this Trial Is About
Transcranial magnetic stimulation (TMS) studies reported consistent and substantial impairments in the central nervous system (CNS) in multiple sclerosis (MS). Studies of peripheral nervous system (PNS) function comprising electromyoneurography (EMNG) reported impairments of the PNS in MS that were less pronounced and inconsistent. Neurophysiological studies are generally small and cross-sectional and with the poor grouping of MS patients according to MS type. The objective of the study is to investigate clinical, neurophysiological, and immunological markers in relapsing-remitting MS patients, and in patients with relapsing-remitting MS treated with immunomodulation. The results of the study may contribute to a better understanding of the pathophysiology of multiple sclerosis and can provide guidance in the diagnosis and treatment of patients with relapsing-remitting MS.
CONDITIONS
Official Title
Investigation of Subclinical Markers of Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of relapsing-remitting multiple sclerosis according to Mc Donald criteria (2005)
- Expanded Disability Status Scale (EDSS) score between 0 and 3.5
You will not qualify if you...
- Presence of metal implants in the body (e.g., pacemaker, dentures)
- New pregnancy (confirmed verbally)
- Recent head trauma
- Unwillingness to sign consent or follow study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Split School of Medicine
Split, Croatia, 21000
Actively Recruiting
Research Team
M
Maja Rogić Vidaković, MSc, PhD
CONTACT
S
Sanda Pavelin, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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