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Age: 18Years +
All Genders
ID07256548

Comparative Evaluation of Machine Learning Algorithms for Predicting Spinal Anesthesia Termination Time

Led by Kocaeli City Hospital · Updated on 2025-12-08

140

Participants Needed

1

Research Sites

2 weeks

Total Duration

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AI-Summary

What this Trial Is About

This research aims to evaluate the use of machine learning (ML) algorithms to predict how long spinal anesthesia will last and when patients will be ready to move after total knee arthroplasty. Spinal anesthesia offers benefits over general anesthesia, such as less blood loss, faster recovery, and fewer complications. Predicting its duration accurately is important for patient safety and better postoperative care. This study investigates how ML models can use patient, surgical, and anesthetic data to provide these predictions and improve perioperative management. Patients in this study will undergo total knee replacement surgery using spinal anesthesia with bupivacaine. Before the procedure, patients are monitored with ECG, blood pressure, and oxygen saturation measurements, and an intravenous line is set up. The spinal anesthesia is administered via a needle between specific vertebrae, injecting bupivacaine to induce numbness for surgery. The study focuses on observing anesthesia duration and patient recovery, using ML models trained on collected clinical data. Participants will be monitored from the time of spinal injection until they fully regain motor function, within about 6 hours. Researchers will assess anesthesia duration and pain levels using scales like the Visual Analogue Scale. Data collected includes vital signs, drug dosages, and surgical details. The study aims to measure how well ML predictions match actual anesthesia duration and patient readiness for mobilization, supporting safer and more personalized care during and after surgery.

CONDITIONS

Brief Title

Machine Learning for Predicting Spinal Anesthesia Duration

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients scheduled for total knee arthroplasty between November 2025 and March 2026 at Kocaeli City Hospital
  • Patients who have provided written informed consent
  • Surgery planned under spinal anesthesia
  • Complete clinical data available during the study
  • Adults aged 18 years or older classified as ASA Physical Status I or II
Not Eligible

You will not qualify if you...

  • Patients converted to or initially operated under general anesthesia
  • Patients requiring postoperative ICU admission after anesthesia
  • Patients with surgical complications preventing postoperative mobilization
  • Patients with cognitive impairment affecting pain assessment
  • Patients with neuropathic pain, multiple sclerosis, or other neuromotor disorders

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - Up to 4 months

Participants are screened for eligibility to participate in the trial.

Spinal Anesthesia and Surgery

Duration - Surgery day

Participants undergo total knee arthroplasty surgery under spinal anesthesia using bupivacaine. Standard monitoring and procedures are performed during surgery.

1 visit (in-person)

Postoperative Monitoring

Duration - Up to 6 hours post-injection

Participants are monitored from the end of spinal anesthesia injection until complete motor recovery, expected within 6 hours, to assess anesthesia duration and readiness for mobilization.

Continuous monitoring during hospital stay

Trial Site Locations

Total: 1 location

1

Kocaeli City Hospital

Kocaeli, İzmit, Turkey (Türkiye), 41000

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Research Team

S

Sıddık Varolgüneş, MD

A

Ahmet Yüksek, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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