Study of Nanosecond Pulsed Field Ablation to Treat Benign Thyroid Nodules in Adults

What this Trial Is About

This research aims to observe the effects of nanosecond pulsed field ablation nsPFA therapy in treating benign thyroid nodules. The study focuses on how the volume of these thyroid nodules changes over time after treatment, as well as the impact on patients health-related quality of life. It also evaluates ultrasound features of the nodules and monitors any complications that may arise from the procedure. Participants scheduled for ultrasound-guided nsPFA as part of their standard clinical care will be observed. The study collects patient-reported outcomes through questionnaires and monitors changes in nodule size and ultrasound characteristics following the nsPFA treatment. The study includes adults aged 18 to 80 years with biopsy-confirmed benign thyroid nodules larger than 2 cm causing compressive symptoms. During the study, participants will complete quality-of-life questionnaires over an average period of one year. Researchers will assess nodule volume changes, ultrasound features, and any minor or major complications related to the treatment. The study is observational, with no experimental treatment assignment, and participation involves routine clinical care and follow-up assessments until study completion.

Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules