Clinical Outcomes and AI Prediction of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules in Adults

What this Trial Is About

Researchers are evaluating the clinical outcomes of ultrasound-guided thermal ablation for treating benign thyroid nodules. This multicenter prospective study also aims to develop and validate an artificial intelligence model to predict the results of this treatment. The study is sponsored by the Chinese PLA General Hospital and focuses on improving care for patients with benign thyroid nodules who may have cosmetic or symptomatic concerns or worries about rapid growth or malignant transformation. The study involves ultrasound-guided thermal ablation procedures, including microwave ablation, radio frequency ablation, and laser ablation, as the experimental intervention. These treatments are performed to reduce the size of thyroid nodules without surgery. Follow-up assessments are planned over an average of six months to monitor treatment effects and any complications. Participants will undergo evaluations of nodule volume reduction, regrowth rates, cosmetic appearance, symptoms, and volume measurements throughout the study. Complications will be tracked during the first week after treatment. The study includes regular monitoring through ultrasound and symptom scoring, with total participation lasting at least six months to assess the long-term effects of the ablation therapy.

The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules