Norwegian Study on Spontaneous Coronary Artery Dissection and Heart Health with One-Year Follow-Up

What this Trial Is About

The Norwegian Spontaneous Coronary Artery Dissection Study NOR-SCAD is a national, multicenter prospective observational study focused on people aged 18 years or older who are hospitalized with spontaneous coronary artery dissection SCAD. Researchers are investigating the risk factors, complications, and major adverse cardiac events MACE that may occur within the first year after SCAD. The study also aims to evaluate the usefulness of coronary CT angiography CTA in diagnosis and follow-up. Participants are enrolled during their initial hospital stay where imaging and blood samples are collected. Follow-up includes scheduled visits at 8 weeks for a control CT scan, at 12 weeks for a thorough physical exam with cardiac assessments, blood tests, and a cardiopulmonary exercise test CPET. A final phone call at 52 weeks checks for clinical events and collects additional information. During the study, participants undergo coronary CTA scans, cardiac exams, blood sampling, genetic testing, and structured questionnaires to assess quality of life. Researchers track major cardiac events and changes seen in imaging over time. The total follow-up lasts 52 weeks, with the main outcome being the occurrence of major adverse cardiac events during this period.

Norwegian Spontaneous Coronary Artery Dissection Study