Open-label Extension Study to Assess Long-term Safety and Effectiveness of QCZ484 Injection Every Six Months in Adults with Hypertension

What this Trial Is About

This trial is for patients with hypertension who have completed previous QCZ484 studies. It aims to gather more information on the long-term safety and effectiveness of QCZ484, a treatment given to lower high blood pressure. The study is an extension phase to build on prior research results for hypertensive patients who successfully finished earlier treatment periods. Participants in this open-label extension study will receive QCZ484 by subcutaneous injection every six months. This single-group, multicenter study offers enrollment to patients at the month 12 visit of their parent study, provided they meet eligibility and have completed their prior treatment safely. The treatment continues to be monitored for up to 66 months to assess ongoing effects and tolerability. During the study, participants will have regular assessments including ambulatory and office blood pressure measurements at baseline and throughout the extension period. Safety will be closely monitored by tracking any adverse events up to 66 months. The study collects data on blood pressure changes and side effects to understand how well QCZ484 works and how safe it remains over the long term. Participation involves scheduled visits aligned with the injection schedule and ongoing health evaluations.

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.