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ID07588165

Observing Pain and Complications During Rapid Sequence Induction for Tracheal Intubation in Surgery Patients Using Analgesia Nociception Index Monitoring

Led by Centre Hospitalier Princesse Grace · Updated on 2026-05-27

150

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are investigating pain responses during rapid sequence induction RSI, a common anesthesia technique used to reduce the risk of aspiration in patients undergoing tracheal intubation. This observational study aims to describe pain levels measured by the Analgesia Nociception Index ANI during RSI and to explore early complications such as desaturation, low blood pressure, and regurgitation, as well as factors linked to pain and complications. The study will analyze 150 patients undergoing RSI in a visceral surgery operating room. Participants receive standard RSI care following French anesthesia guidelines, with anesthesiologists choosing induction drugs such as hypnotics, opioids, and neuromuscular blockers based on routine practice. During the procedure, additional non-invasive electrodes placed on the chest monitor ANI to assess pain responses. The study records various clinical data including heart rate, blood pressure, oxygen levels, intubation devices used, and postoperative sore throat occurrence. Throughout the study, patients are monitored for 5 minutes following RSI for changes in ANI and hemodynamic parameters. Data on early complications and intubation success are collected, alongside patient characteristics and medication use. Follow-up continues for 24 hours to assess sore throat presence. The study involves no extra examinations beyond standard care and aims to provide detailed pain and complication profiles during RSI.

CONDITIONS

Brief Title

Pain Assessment During Rapid Sequence Induction

Research Team

R

Remy WIDEHEM

C

Celine DUGOURD

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