Actively Recruiting

Age: 18Years - 65Years
All Genders
ID07545499

Comparison of Respiratory Muscle Strength, Physical Activity Level, and Dietary Habits in Individuals With Post-COVID-19 Syndrome Having Different Circadian Rhythms

Led by Hacettepe University · Updated on 2026-04-22

50

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how circadian rhythms, or chronotypes, affect people who have ongoing symptoms after COVID-19 infection, known as post-COVID-19 syndrome. This condition includes fatigue, reduced physical activity, and breathing difficulties. The study aims to compare respiratory muscle strength, physical activity, and dietary habits among individuals with different chronotypes: morning, intermediate, and evening types. Genetic testing of the CLOCK gene will also be done to better understand circadian rhythm differences. This observational study includes adults aged 18 to 65 years diagnosed with post-COVID-19 syndrome. Participants will be grouped by their chronotype using a questionnaire. Researchers will measure respiratory muscle strength using breathing tests and devices, physical activity through questionnaires, and dietary intake by 24-hour recall. Additional assessments include sleep quality, fatigue, gastrointestinal symptoms, and genetic analysis from blood samples. Participants will complete various questionnaires and physical tests during a single visit. Respiratory muscle strength, endurance, physical activity, diet, sleep quality, and fatigue severity will be evaluated. Blood samples will be collected for genetic analysis. The study will help clarify how circadian rhythms relate to symptoms and lifestyle in post-COVID-19 syndrome, potentially guiding personalized rehabilitation approaches.

CONDITIONS

Brief Title

Physical Functions and Lifestyle Behaviours in Post-COVID-19 Syndrome Based on Circadian Rhythms

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Post-COVID-19 Syndrome
  • Aged between 18-65 years
  • Able to read and understand Turkish
  • Voluntary participation
  • Classified as Post-Covid Functional Status Scale (PCFS) grade 2-3
  • Clinically stable condition
  • No uncontrolled comorbidities (e.g., hypertension, diabetes under control)
  • No orthopedic or neurological conditions affecting exercise testing
Not Eligible

You will not qualify if you...

  • Recent myocardial infarction or pulmonary embolism
  • Severe uncontrolled chronic diseases
  • Neurological or orthopedic conditions limiting mobility
  • Psychiatric or neurological disorders affecting cooperation or test compliance
  • Inability to complete assessments

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo assessments to evaluate respiratory muscle strength, physical activity levels, dietary habits, sleep quality, fatigue severity, gastrointestinal symptoms, and chronotype classification.

1 visit (in-person)

Sample Collection

Duration - 1 day

Blood samples are collected for genetic analysis of the CLOCK gene polymorphism to objectively assess circadian rhythm differences.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Hacettepe University Faculty of Physical Therapy and Rehabilitation

Ankara, Altindağ, Turkey (Türkiye), 06100

Actively Recruiting

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Research Team

E

Ebru Çalık, Professor

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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