Actively Recruiting

Phase Not Applicable
Age: 60Years - 80Years
All Genders
Healthy Volunteers
NCT05400733

Prandial Metabolic Phenotype in Adults

Led by Texas A&M University · Updated on 2025-10-01

50

Participants Needed

1

Research Sites

218 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Previous studies suggest that changes in metabolism due to the effects of aging might serve as a potential for therapeutic agents. The investigating lab developed a pulse method combining multiple stable isotopes to study multiple metabolic pathways in the same individual simultaneously. By measuring whole-body metabolism in a large group of older adults, the investigators may be able to unravel age-related deterioration in protein turnover (synthesis and breakdown) that contributes to impaired functional capacity. Metabolic profiles could explain differences in pathways in the aging process with special interest in metabolism of amino acids as they have been associated with aging-related disorders.

CONDITIONS

Official Title

Prandial Metabolic Phenotype in Adults

Who Can Participate

Age: 60Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 60 and 80 years, inclusive
  • Stable body weight (within ±5%) for the past 3 months
  • Overall satisfactory health based on medical history, physical exam, and lab tests
  • Ability to walk, sit, and stand independently or with walking aids
  • Ability to lie in supine or elevated position for up to 7 hours
  • Willingness and ability to follow the study protocol
Not Eligible

You will not qualify if you...

  • Current diagnosis of cancer
  • History of untreated metabolic diseases including liver or kidney disorders
  • Presence of acute illness or unstable chronic illness
  • Fever within the last 3 days
  • Use of short course oral corticosteroids within 4 weeks before study day
  • Possible pregnancy
  • Inability or unwillingness to give informed consent or follow study requirements
  • Participation in another clinical trial that conflicts with this study
  • Any condition identified by the investigator or nurse during screening that may interfere with the study or participant safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Human Clinical Research Facility

College Station, Texas, United States, 77843

Actively Recruiting

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Research Team

M

Marielle Engelen

CONTACT

S

Savanah Knezek

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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