Pregnancy-Related Aortic Dissection in China A National Study Tracking Mothers and Newborns

What this Trial Is About

Researchers are conducting a national multicenter observational study in China to understand pregnancy-related aortic dissection, a serious complication affecting mothers and newborns. This study tracks mothers and their babies to evaluate outcomes related to this condition, including associated syndromes such as Marfan, Loeys-Dietz, and vascular Ehlers-Danlos syndromes. The study aims to provide important information on maternal and neonatal health during and after pregnancy complicated by aortic dissection. Participants in this study will be observed based on their treatment strategies, which may include medication or surgery. The choice of intervention, such as delivery or surgical procedures, depends on the pregnancy stage, type of aortic dissection, and decisions made by the patient and her family. The study focuses on cases where aortic dissection occurs during pregnancy, labor, or up to 12 weeks postpartum. During the study, participants will be monitored for early-term mortality of mothers and newborns within 30 days after treatment, as well as long-term mortality up to about three years. Researchers will also track maternal adverse events and any developmental abnormalities in newborns over this period. The total participation duration spans from pregnancy through long-term follow-up, involving evaluations that include imaging confirmations and health assessments of both mother and child.

PregnAncy-Related Aortic DISsEction in China