Using Machine Learning and Lung Ultrasound to Predict Postoperative Pulmonary Complications in Adults Undergoing Elective Surgery with General Anesthesia
Led by Britta Trautwein · Updated on 2026-05-08
512
Participants Needed
1
Research Sites
13 weeks
Total Duration
AI-Summary
What this Trial Is About
Postoperative pulmonary complications POPC are common after general anesthesia and cause increased illness and death in surgical patients. This research aims to improve early detection of POPC by developing a machine learning algorithm that uses standard clinical data and lung ultrasound images collected after surgery. The study will include 512 adults undergoing planned surgery with general anesthesia to better predict who is at risk of developing these complications before symptoms appear.
All patients will have their routine clinical data collected during surgery and will receive a standardized lung ultrasound in the recovery room. Follow-up clinical exams will occur on postoperative days 1, 3, and 7 to check for signs of POPC using standardized criteria. The collected data, including ultrasound images, will be used to train and evaluate a neural network-based machine learning model to predict postoperative lung complications.
Participants will be monitored through clinical exams and lung sonography after surgery, with data stored securely for analysis. Researchers will measure the number of patients developing POPC by day 7 or discharge. The models predictive accuracy will be compared to existing risk scores. This study may help improve patient outcomes by enabling earlier detection and targeted prevention of lung complications after surgery.
CONDITIONS
Brief Title
PrEventing PostoPERative Pulmonary Complications by Establishing a MachINe-learning assisTed Approach
Research Team
B
Britta Trautwein, MD
S
Simone Kagerbauer, PD
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Participants are screened for eligibility to participate in the trial.
1 visit (in-person) to confirm eligibility before surgery
Diagnostic Evaluation
Duration - Immediately postoperative
Participants undergo standardized lung sonography in the recovery room after surgery to collect imaging data.
1 visit (in-person) in the recovery room after surgery
Long-term Monitoring
Duration - 7 days after surgery
Participants are visited on the ward on postoperative days 1, 3, and 7 for clinical examination to detect postoperative pulmonary complications.
3 visits (in-person) on postoperative days 1, 3, and 7
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators.
Ana Fernandez-Bustamante, Gyorgy Frendl, Juraj Sprung...
Do ARISCAT scores help to predict the incidence of postoperative pulmonary complications in elderly patients after upper abdominal surgery? An observational study at a single university hospital.
Preventing postoperative pulmonary complications by establishing a machine-learning assisted approach (PEPPERMINT): Study protocol for the creation of a risk prediction model.