Actively Recruiting
Prospective Cohort Study on Fuzheng Yangxin Prescription for Rapid Rehabilitation of Patients with Qi-Yin Deficiency Syndrome After Coronary Artery Bypass Grafting
Led by Peking University Third Hospital · Updated on 2026-05-08
300
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ischemic heart disease, caused by narrowing or blockage of coronary arteries, is a leading cause of death worldwide and significantly affects the health of Chinese residents. Coronary artery bypass grafting (CABG) is considered the gold standard treatment for complex coronary artery disease and is increasingly used, especially in an aging population. Despite its benefits, CABG surgery can cause physical and psychological challenges during early recovery, including complications such as myocardial infarction, heart failure, and atrial fibrillation. This study aims to evaluate the effectiveness and safety of the Fuzheng Yangxin prescription, a traditional Chinese medicine, in improving recovery after CABG in patients with Qi-Yin deficiency syndrome. Participants will be observed in a prospective cohort study to assess the impact of Fuzheng Yangxin prescription compared with placebo on postoperative rehabilitation. The study focuses on patients who have undergone CABG surgery and have a diagnosis of Qi-Yin deficiency after the operation. The research seeks to develop a combined Chinese and Western medicine treatment strategy to enhance recovery, improve quality of life, and reduce complications following cardiac surgery. During the study, researchers will monitor participants' health using Seattle Angina Questionnaire (SAQ) scores at 7 days post-ligation and at 12 months, along with a perioperative safety index at 14 days. These measures will help evaluate the recovery progress and safety of the treatment. The study will also contribute to establishing guidelines for integrated postoperative care and support the wider adoption of combined therapies in cardiac surgery rehabilitation. Total participation duration and follow-up will align with these assessment timepoints.
CONDITIONS
Brief Title
Prospective Cohort Study on Fuzheng Yangxin Prescription For Rapid Rehabilitation of Patients With Qi-Yin Deficiency Syndrome After Coronary Artery Bypass Grafting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who received coronary artery bypass surgery with syndrome differentiation of Qi-Yin deficiency after operation
You will not qualify if you...
- Patients allergic to Fuzheng Yangxin Fang granules
- Patients with postoperative cold and fever
- Patients with severe postoperative hepatic and renal insufficiency
- Patients with concurrent valvular surgery or other cardiac surgery
- Patients with end-stage malignant tumor
- Patients with uncontrolled infection
- Patients with bleeding
- Patients with progressive degenerative systemic disease
- Patients with severe brain injury
- Patients with multiple organ failure
- Patients with other vital organ dysfunction such as severe liver impairment, severe heart failure or cardiogenic shock
- Patients unable to tolerate surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 14 days
Participants receive either the Fuzheng Yangxin prescription or a placebo after coronary artery bypass grafting to support rapid rehabilitation and recovery.
Visits during the 14-day perioperative period
Duration - 12 months
Participants are monitored for recovery progress and quality of life up to 12 months after surgery.
Follow-up visits to assess health status and SAQ scores
Trial Site Locations
Total: 1 location
1
Peking university third hospital
Beijing, Beijing Municipality, China, 100191
Actively Recruiting
Research Team
Y
Yichen Gong Doctor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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