Actively Recruiting

Age: 18Years +
All Genders
ID04538859

A Prospective Study of Factors Related to Exacerbation and Mortality of Non-cystic Fibrosis Bronchiectasis in Hong Kong

Led by Chinese University of Hong Kong · Updated on 2020-09-04

400

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Bronchiectasis is a lung condition marked by repeated flare-ups, occurring 1.5 to 6.5 times per patient each year. These flare-ups increase the risk of hospital admissions and lead to high healthcare costs. A previous local study found that most patients with bronchiectasis, primarily females, had idiopathic disease with significant hospitalizations and mortality rates. This research aims to update the understanding of bronchiectasis prevalence, causes, symptoms, and outcomes to improve future management plans. This observational study follows adults diagnosed with bronchiectasis confirmed by a high-resolution CT scan. Participants must be clinically stable for at least four weeks before joining and will be monitored over five years without any interventional treatment. The study will record the number of bronchiectasis flare-ups and mortality rates during this period to better understand disease progression. Participants will be observed for five years, during which their frequency of exacerbations and survival will be tracked. The study will collect data on symptom changes, hospitalizations, and treatment needs. This long-term follow-up aims to provide comprehensive information to guide care strategies and reduce the impact of bronchiectasis on patients' health and healthcare resources.

CONDITIONS

Brief Title

A Prospective Study of Factors Related to Exacerbation and Mortality of Non-cystic Fibrosis Bronchiectasis in Hong Kong

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Clinically stable for at least 4 weeks prior to enrollment with no symptoms of exacerbation or need for antibiotic therapy
  • Diagnosis of bronchiectasis confirmed by high-resolution computed tomography scan
Not Eligible

You will not qualify if you...

  • History of cystic fibrosis, hypogammaglobulinemia, or allergic bronchopulmonary aspergilosis
  • Unable to give consent to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Long-term Monitoring

Duration - 5 years

Participants are observed to track bronchiectasis exacerbations and mortality over time.

Trial Site Locations

Total: 1 location

1

Chinese University of Hong

Hong Kong, Please Select, Hong Kong

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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