Adapting After Discharge From Allogeneic Stem Cell Transplant: Dyadic Intervention to Improve Patient and Family Caregiver Management

What this Trial Is About

Researchers are evaluating two brief psychosocial interventions to support patients who have undergone stem cell transplant and their family caregivers in managing medical regimens after hospital discharge. This randomized clinical trial aims to find out if either intervention improves psychological well-being and health-related outcomes for both patients and caregivers. The study is led by the University of Pittsburgh and focuses on the post-discharge period following allogeneic hematopoietic cell transplantation. Participants will be randomly assigned to one of two groups: the Dyadic Problem Solving Training (DPST) group or the Supportive Care group. Both interventions consist of four sessions delivered via live video conferencing. DPST teaches problem-solving skills to help manage the medical regimen, while Supportive Care provides emotional and practical support. Each group includes 52 patient-caregiver pairs, and the interventions aim to improve adherence and perceived task efficacy. Participants and their caregivers will complete questionnaires before the intervention and at 1, 5, 12, and 24 weeks afterward. Researchers will assess health habits, perceived task efficacy, medication levels, healthcare use, mood, anxiety, relationship adjustment, and caregiver reactions. The study includes close monitoring through repeated assessments over 24 weeks, allowing detailed evaluation of how the interventions affect daily management and well-being post-transplant.

Psychosocial and Behavioral Intervention for Stem Cell Transplant Patients and Their Family Caregivers