Actively Recruiting

Phase 3
Age: 18Years +
FEMALE
NCT05551104

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension

Led by Loma Linda University · Updated on 2026-02-04

500

Participants Needed

1

Research Sites

238 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.

CONDITIONS

Official Title

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female

  • Women who develop postpartum hypertension* after delivery of the placenta or chronic hypertensive postpartum women who require medication for blood pressure control.

    • Postpartum hypertension requiring treatment are defined as systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than or equal to 90mmHg on at least 2 occasions at least 4 hours apart, or systolic blood pressure greater than or equal to 160mmHg or diastolic blood pressure greater than 110mmHg sustained for more than 15 minutes.
Not Eligible

You will not qualify if you...

  • History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema
  • Contraindication to either Nifedipine or Labetalol
  • HR <60 or >110
  • Native language other than English or Spanish

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Loma Linda University Health

Loma Linda, California, United States, 92350

Actively Recruiting

Loading map...

Research Team

A

Ashra Denise B Tugung, BSc

CONTACT

N

Nikia Gray-Hutto, RN, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension | DecenTrialz