Cardiac Surgery in Women in the Current Era: What Are the Gaps in Care?
Leslie Cho, Melina R Kibbe, Faisal Bakaeen...
https://pubmed.ncbi.nlm.nih.gov/34606298Actively Recruiting
Led by Jennifer Breel · Updated on 2024-08-15
10000
Participants Needed
1
Research Sites
52 weeks
Total Duration
Researchers are studying the differences between females and males undergoing cardiac surgery to understand how sex-specific factors affect perioperative care and outcomes. The study focuses on various perioperative elements such as body weight adaptation, medical history, drug processing, blood transfusions, blood clotting, heart-lung machine use, heart function, medication needs, risk and outcome scores, as well as short-term and long-term morbidity and mortality. This research aims to identify factors that may cause worse outcomes in females after cardiac surgery and improve their care. The study compares female and male patients undergoing all types of cardiac surgery by collecting and analyzing a wide range of perioperative data. This observational study does not involve experimental treatments but reviews existing records of patients treated between January 1998 and June 2021 at a specific medical center. The goal is to build a database of perioperative parameters to find differences that may require tailored care pathways for females. Participants are patients aged 18 years and older who have undergone cardiac surgery during the specified period. The research team will evaluate mortality rates at multiple time points: 30 days, 1 year, 5 years, and 20 years after surgery. They will also assess postoperative complications at 30, 90, and 365 days, and develop a predictive risk score based on composite outcomes within 30 days. This long-term follow-up aims to enhance understanding of sex-specific risks and improve recovery after cardiac surgery.
CONDITIONS
SEx-specific Differences in Cardiac Surgery Patients (SECS).
You may qualify if you...
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Hospital stay duration following surgery
Participants undergo cardiac surgery and receive immediate post-operative care.
Hospital visits during surgery and immediate recovery
Duration - Up to 20 years postoperatively
Participants are monitored for post-operative complications and mortality over short and long term after surgery.
Follow-up visits at 30 days, 90 days, 1 year, 5 years, and up to 20 years postoperatively
Total: 1 location
1
Academic Medical Center
Amsterdam, North Holland, Netherlands, 1105AZ
Actively Recruiting
J
Jennifer S Breel, MSc
S
Susanne Eberl, PhD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Leslie Cho, Melina R Kibbe, Faisal Bakaeen...
https://pubmed.ncbi.nlm.nih.gov/34606298Lauren Kari Dixon, Ettorino Di Tommaso, Arnaldo Dimagli...
https://pubmed.ncbi.nlm.nih.gov/34520795Danop Nanegrungsunk, Shayna Patel, Thomas Jan...
https://pubmed.ncbi.nlm.nih.gov/34776353Sanne A E Peters, Jolanda Kluin
https://pubmed.ncbi.nlm.nih.gov/34524421