Actively Recruiting
The Effects of Short-Term Circuit Strength Training Intervention on Muscle Mass, Metabolic Health, Balance, Quality of Life, and Inflammaging in Sedentary Postmenopausal Women
Led by Loma Linda University · Updated on 2026-06-08
46
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the effects of circuit strength training on muscle mass, metabolic health, balance, quality of life, and inflammation in sedentary postmenopausal women aged 50 to 75. This study aims to provide evidence on how this exercise approach might improve both physical and psychosocial well-being in this population. The trial uses a randomized controlled design to assess changes in muscle strength, inflammatory markers, balance, functional capacity, and quality of life over 10 weeks. Participants are randomly assigned to either an exercise group or a non-exercise control group. The exercise group completes circuit strength training sessions three times a week for eight weeks. Each session lasts about 45 minutes and includes a warm-up, two sets of high-intensity exercises targeting major muscle groups, and a cool-down. Exercise intensity increases progressively every two weeks. The control group maintains their sedentary lifestyle and usual diet throughout the study. During the trial, participants will undergo various assessments including body composition using IN-BODY technology, muscle mass measured by ultrasound, grip and quadriceps strength tests, balance evaluation, aerobic capacity via the 6-minute walk test, and respiratory strength. Inflammatory markers will be monitored through blood tests. Psychosocial well-being will be assessed using questionnaires on quality of life, sleep quality, mood, and fall risk. Sleep and heart rate variability will be tracked using Fitbit devices. Data collection occurs at the start and end of the 10-week period to measure changes. Safety and adherence will be monitored throughout the study.
CONDITIONS
Brief Title
Short-term Circuit Training on Muscle Mass and Quality of Life in Sedentary Postmenopausal Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female aged between 50 and 75 years
- Self-reported postmenopausal status with no menstruation for at least 12 months
- Physically capable of participating in an exercise program
- No structured resistance or aerobic training in the past 6 months
You will not qualify if you...
- Moderate or high physical activity level based on IPAQ (more than 600 MET-minutes/week)
- Diagnosis of any condition that prevents safe exercise, such as significant cardiovascular, orthopedic, or neuromuscular issues
- Regular use of medications that may affect study outcomes, like corticosteroids or immunosuppressants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 week
Participants complete initial baseline tests including body composition, balance, strength, muscle mass, respiratory strength, aerobic capacity, heart rate variability, sleep quality, psychosocial questionnaires, and blood tests for inflammatory markers. Those in the exercise group also attend two additional visits to introduce the exercise, evaluate movements, and determine maximum exercise capacity.
3 visits for exercise group; 1 visit for control group (all in-person)
Duration - 8 weeks
The exercise group participates in circuit strength training sessions approximately 45 minutes long, three times a week for 8 weeks. The control group maintains their usual sedentary lifestyle without changes in activity or diet.
3 exercise sessions per week for exercise group; no visits required for control group
Duration - 1 week
After completing the 8-week exercise protocol, all participants visit the research laboratory for final data collection and retesting. The exercise protocol is shown to the control group during this visit.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Loma Linda University
Loma Linda, California, United States, 92354
Actively Recruiting
Research Team
E
Everett Lohman, Dsc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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