Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05215353

A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-02-02

368

Participants Needed

3

Research Sites

259 weeks

Total Duration

On this page

Sponsors

M

Memorial Sloan Kettering Cancer Center

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The researchers are doing this study to compare how music therapy and cognitive behavioral therapy, given virtually, may be able to reduce anxiety in people who have had cancer. In addition, this study will see if certain factors affect how well participants respond to music therapy or cognitive behavioral therapy. For example, the researchers will see if personal characteristics (like age, sex, race, and education) and ways of thinking (like expectations of therapy) may affect how well participants respond.

CONDITIONS

Official Title

A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • English- or Spanish-speaking
  • 18 years or older
  • Prior cancer diagnosis of any type or stage
  • Free of active cancer or stable disease with no progression
  • Anxiety score of 8 or higher on the Hospital Anxiety and Depression Scale (HADS)
  • Anxiety symptoms lasting at least one month
  • Willing to follow all study procedures including randomization to music therapy or cognitive behavioral therapy
  • Have access to Zoom and a quiet, private location
  • For advanced cancer sub-study: specific advanced cancers, currently receiving treatment or active surveillance, Karnofsky performance score 60 or higher, expected survival greater than 6 months
  • For group music therapy sub-study: same as main criteria with willingness to follow study procedures
Not Eligible

You will not qualify if you...

  • Completed active cancer treatment less than one month before enrollment (except maintenance hormonal or targeted therapies)
  • Active suicidal thoughts, bipolar disorder, schizophrenia, or substance abuse
  • Cognitive impairment indicated by a score of 10 or higher on the Blessed Orientation-Memory-Concentration test
  • Received seven or more sessions of music therapy or cognitive behavioral therapy for anxiety in the last six months
  • Unable to provide informed consent
  • For advanced cancer sub-study: plan for psychotherapy or changes in anxiety medication within the next 8 weeks or recent changes in past 4 weeks
  • Prior receipt of music therapy within the past six months

AI-Screening

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Trial Site Locations

Total: 3 locations

1

Baptist Alliance MCI

Miami, Florida, United States, 33143

Actively Recruiting

2

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

3

Drexel University

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

J

Jun Mao, MD, MSCE

CONTACT

K

Kevin Liou, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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