Correlation Between Types of Tuberculosis, Spirometry Result, and Functional Capacity Based on the 6-Minute Walk Test (6MWT) in Adolescents With Post-Tuberculosis Lung Disease

What this Trial Is About

Post-Tuberculosis Lung Disease (PTLD) affects adolescents who have recovered from pulmonary tuberculosis, causing ongoing respiratory problems like reduced lung volumes and impaired exercise capacity. This condition can lead to long-term difficulties in daily activities and significantly reduced lung function in some patients. This study aims to analyze how different types of tuberculosis relate to lung function measured by spirometry and physical capacity assessed by the 6-Minute Walk Test (6MWT) in adolescents with PTLD. This is an observational study using a cross-sectional design conducted at Hasan Sadikin Hospital in Bandung from March to May 2026. Eligible participants are adolescents aged 10 to 18 years diagnosed with PTLD by a pediatrician and able to perform the 6MWT. Participants will undergo spirometry tests following standardized guidelines to measure lung function, including Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC). Functional capacity will be evaluated by measuring the distance walked in six minutes and calculating metabolic equivalents (METs). During the study, participants will complete lung function tests and the 6MWT in a controlled environment. Researchers will collect and analyze data to explore correlations between tuberculosis type, spirometry results, and physical capacity. The primary outcomes include changes in the 6MWT distance (measured in METs), FEV1, and FVC over 12 weeks. The study emphasizes participant safety, informed consent, and confidentiality. Results aim to improve understanding of PTLD recovery and inform rehabilitation approaches for affected adolescents.

TB Type and Spirometry Result vs. Functional Capacity Based on 6MWT in People With Post-TB Lung Disease