Actively Recruiting
Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy
Led by Peking University Third Hospital · Updated on 2023-08-02
156
Participants Needed
1
Research Sites
282 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa and is considered a precancerous condition. It is characterized by white reticular changes in the oral mucosa, which can progress to erosions and cause pain in severe cases. The pathogenesis of OLP is still unclear, but it is believed to be a T-lymphocyte-mediated autoimmune disease. Currently, only symptomatic treatments are available, and there is no definitive cure. In this project, we plan to use TCM differentiation to categorize OLP patients and conduct a randomized controlled clinical trial to demonstrate the enhanced therapeutic effect of paeoniflorin combined with photodynamic therapy for OLP. The implementation of this project will provide new insights into the clinical management of OLP, improve our understanding of the treatment mechanisms, and have important theoretical and clinical implications.
CONDITIONS
Official Title
Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with oral lichen planus
- Male or female patients older than 18 years of age
- Patients willing to participate with signed informed consent
You will not qualify if you...
- Pregnant or lactating women
- Patients with serious systemic diseases of the heart, lung, liver, or kidney, or tumors
- Patients unwilling to participate in the experiment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking University Third Hospital
Beijing, China
Actively Recruiting
Research Team
Z
Zhihui Zhang, Dr.
CONTACT
L
Lin Zeng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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