Development and validation of the Affective Self Rating Scale for manic, depressive, and mixed affective states.
Mats Adler, Benny Liberg, Stig Andersson...
https://pubmed.ncbi.nlm.nih.gov/18569776Actively Recruiting
Age: 18Years +
All Genders
ID05827406
A Usable Support System for Psychiatric Diagnosis and Follow-up in Adult Psychiatry and Primary Care (ASPP)
Led by Karolinska Institutet · Updated on 2023-10-18
2200
Participants Needed
5
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to develop and scientifically evaluate a set of self-assessment scales to support psychiatric diagnostics and follow-up in adults with psychiatric problems. These scales collect detailed information on symptoms, age of onset, symptom development, relation to external stress, and the impact on function and suffering. The goal is to create validated tools that help clinicians classify psychiatric conditions more effectively using fewer, optimized questions. Participants are recruited consecutively from five specific sites and asked to complete various item sets measuring relevant psychiatric symptoms. The study involves multiple groups, each responding to different item sets that are refined and validated over time using statistical methods. After optimizing individual item sets, the scales are combined and further tested to reduce the number of questions and dimensions needed for accurate assessment. Participants will answer sets of questions about their symptoms and experiences during multiple recruitment phases. Researchers analyze the responses to refine the scales, aiming for concise and reliable tools. The main outcome measure is the Scalability H index, which assesses the measurement quality of the scales. Participation involves completing questionnaires, with ongoing evaluation to improve the diagnostic support system.
CONDITIONS
Brief Title
A Useful Support System for Psychiatric Diagnostics and Follow-up in Adult Psychiatry and Primary Care (ASPP)
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patients with psychiatric problems
- Age 18 years or older
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
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1
2
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Monitoring
Duration - Multiple recruitment and assessment phases over the course of the study until 2026-12-31
Participants respond to sets of self-assessment scales measuring psychiatric symptoms and behavior. These assessments are used to develop and validate optimized item sets for psychiatric diagnostics and follow-up.
1 to 2 visits depending on item set and cohort assignment
Trial Site Locations
Total: 5 locations
1
Wemind
Stockholm, Sweden, 112 34
Actively Recruiting
2
Prima vuxen
Stockholm, Sweden, 117 43
Actively Recruiting
3
Gustavsbergs vårdcentral
Stockholm, Sweden, 134 40
Actively Recruiting
4
Stuvsta vårdcentral
Stockholm, Sweden, 141 40
Actively Recruiting
5
Psykiatri Sydväst
Stockholm, Sweden, 141 86
Actively Recruiting
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Research Team
M
Mats O Adler, MD
B
Benny S Liberg, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
14
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Published Research Related To This Trial
An IRT validation of the Affective Self Rating Scale.
Mats Adler, Ulf Brodin
https://pubmed.ncbi.nlm.nih.gov/21539501Symptoms and treatment of bipolar patients in Sweden.
Mats Adler, Lena Backlund, Gunnar Edman...
https://pubmed.ncbi.nlm.nih.gov/22432978An item response theory evaluation of three depression assessment instruments in a clinical sample.
Mats Adler, Jerker Hetta, Göran Isacsson...
https://pubmed.ncbi.nlm.nih.gov/22721257Randomized clinical trials underestimate the efficacy of antidepressants in less severe depression.
G Isacsson, M Adler
https://pubmed.ncbi.nlm.nih.gov/22176585A comparison of three methods of assessing differential item functioning (DIF) in the Hospital Anxiety Depression Scale: ordinal logistic regression, Rasch analysis and the Mantel chi-square procedure.
Isobel M Cameron, Neil W Scott, Mats Adler...
https://pubmed.ncbi.nlm.nih.gov/24848597Longitudinal Cortical Thickness Changes in Bipolar Disorder and the Relationship to Genetic Risk, Mania, and Lithium Use.
Christoph Abé, Benny Liberg, Jie Song...
https://pubmed.ncbi.nlm.nih.gov/31635761Brain change trajectories that differentiate the major psychoses.
Benny Liberg, Christoffer Rahm, Anita Panayiotou...
https://pubmed.ncbi.nlm.nih.gov/27208657Functional and structural alterations in the cingulate motor area relate to decreased fronto-striatal coupling in major depressive disorder with psychomotor disturbances.
Benny Liberg, Paul Klauser, Ian H Harding...
https://pubmed.ncbi.nlm.nih.gov/25538633