Actively Recruiting
Accuracy of EEG Slow Wave Activity in Predicting Favourable Outcome in Patients With Hypoxic Brain Injury - A Substudy of STEPCARE Trial
Led by University of Helsinki · Updated on 2024-08-28
300
Participants Needed
4
Research Sites
187 weeks
Total Duration
On this page
Sponsors
U
University of Helsinki
Lead Sponsor
U
University of Oulu
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an observational substudy embedded in the STEPCARE Trial. The study involves EEG analysis, covered by the ethics approval of STEPCARE Trial. The investigators aim to compare the accuracy of a continuously measured algorithm-based EEG index, C-Trend Index, with retrospective visual analysis of continuous EEG in predicting favorable functional outcome in adult patients treated in intensive care units after out-of-hospital cardiac arrest. The primary hypothesis is that the accuracy of C-Trend Index has at least 10% better accuracy in predicting favorable outcome than the visual analysis of cEEG, when assessed early, 9-12 hours after return of spontaneous circulation (ROSC).
CONDITIONS
Official Title
Accuracy of EEG Slow Wave Activity in Predicting Favourable Outcome in Patients With Hypoxic Brain Injury - A Substudy of STEPCARE Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Out-of-hospital cardiac arrest (OHCA) with sustained return of spontaneous circulation (ROSC)
- Unconscious after ROSC
- No limitations to full life support
- Randomized to STEPCARE Trial in a participating center with Brainstatus device available
You will not qualify if you...
- Under 18 years of age
- Previously randomized to STEPCARE Trial
- Trauma or hemorrhage as the cause of cardiac arrest
- Suspected or confirmed intracerebral hemorrhage
- Allergy to adhesive material
- Damaged skin at the frontal-temporal area preventing electrode attachment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Helsinki University Hospital
Helsinki, Finland, 00290
Actively Recruiting
2
Kuopio University Hospital
Kuopio, Finland
Actively Recruiting
3
Tampere University Hospital
Tampere, Finland
Actively Recruiting
4
Skane University Hospital
Lund, Sweden
Actively Recruiting
Research Team
J
Johanna Hästbacka, a/c professor
CONTACT
J
Jukka Kortelainen, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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