Comparing Automatic and Manual Ventilation During Emergency Resuscitation for Out-of-Hospital Cardiac Arrest Patients

What this Trial Is About

This research aims to compare two ventilation strategies used before hospital arrival in patients who experience out-of-hospital cardiac arrest OHCA. The study evaluates how automatic ventilation compares to manual ventilation in terms of patient survival, neurological outcomes, and quality of resuscitation. Researchers want to understand whether automatic ventilation affects the chance of return of spontaneous circulation ROSC and overall prognosis compared to manual ventilation provided by emergency medical technicians. Participants will be randomly assigned to one of two groups after placement of an advanced airway. In the automatic ventilation group, a pneumatic ventilator device called Meditech MICROVENT RESUSCITATOR is connected to provide breaths every 6 seconds with set pressure and volume. In the manual ventilation group, emergency medical technicians use a bag valve mask to provide breaths every 6 seconds manually. The device settings and ventilation intervals are controlled differently between the groups to compare the two methods. During the study, researchers will monitor outcomes such as the percentage of patients achieving ROSC within 2 hours, sustained ROSC at 24 hours, survival to hospital discharge up to 90 days, and neurological status after discharge. They will also measure chest compression fraction, intravenous catheter placement, epinephrine use, technician satisfaction during dispatch, and incidence of pneumothorax. The study duration and follow-up extend up to 90 days after hospital discharge to assess longer-term outcomes.

Automatic Ventilation in Prehospital Resuscitation on OHCA