Actively Recruiting

All Genders
Healthy Volunteers
ID01746537

Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

Led by The Cleveland Clinic · Updated on 2026-03-04

1500

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

This research aims to explore the use of optical coherence tomography (OCT) scans to analyze inflammation in the front part of the eye, specifically in people with uveitis. The study is observational, meaning it observes and collects data without testing a new treatment. It investigates whether OCT can effectively image and grade the level of inflammation in eyes with both active and inactive uveitis. Participants will have OCT scans taken of the anterior chamber of their eyes to capture detailed images of inflammation. The study does not involve any treatment or intervention but focuses on gathering imaging data. This approach helps determine if OCT can be a reliable tool for assessing eye inflammation. During the study, participants will undergo the OCT imaging process, and researchers will evaluate these images to measure the degree of inflammation. The main outcome is to objectively assess inflammation levels over one year. Participants may also be asked about their ability to provide informed consent. The study is conducted over several years, allowing careful observation of inflammation patterns in uveitis.

CONDITIONS

Brief Title

Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting to Cole Eye Institute with uveitis
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent, including non-English speakers and those with cognitive or mental impairments
  • Severe corneal opacities preventing imaging of the anterior chamber

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 1 year

Participants undergo optical coherence tomography (OCT) imaging to assess anterior chamber inflammation.

Periodic visits for OCT imaging over one year

Trial Site Locations

Total: 1 location

1

Cole Eye Institute

Cleveland, Ohio, United States, 44195

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Research Team

S

Sunil K Srivastava, M.D.

K

Kimberly M Baynes, BSN, RN

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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