Actively Recruiting

Age: 1Day - 49Years
All Genders
Healthy Volunteers
ID05154331

Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)

Led by University of North Carolina, Chapel Hill · Updated on 2025-05-30

7500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of North Carolina, Chapel Hill

Lead Sponsor

B

Bill and Melinda Gates Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are conducting a prospective longitudinal study in Lusaka, Zambia, to better understand the pregnancy rates and outcomes among women of reproductive age. The study aims to explore the health and well-being of women before, during, and after pregnancy, as well as the factors that may affect adverse outcomes during these reproductive periods. This information is intended to improve care for mothers and their children in the future. Women aged 15 to 49 years who live in the study area will be enrolled and followed for up to three years. Participants will be visited every three months, during which their medical records will be reviewed, a brief physical exam and urine pregnancy test will be conducted, and they will answer survey questions. Women will also collect vaginal swabs themselves for future testing. Infants born to participating women during the study will also be included. During the study, researchers will collect data on pregnancy rates, term live births, and infant mortality, measured over the entire enrollment period up to 36 months. The study involves regular health assessments and surveys to monitor participants' well-being. Safety and data interpretation will be closely monitored, considering any social or medical factors that could affect participation. Total participation may last up to three years, with quarterly visits to support continuous observation and data collection.

CONDITIONS

Brief Title

Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)

Who Can Participate

Age: 1Day - 49Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Verbal consent obtained from head-of-household
  • Women aged 15 to 49 years
  • Must be a member of the household in the study area
  • Willing and able to provide written informed consent or assent with next-of-kin consent
  • Willing to undergo study procedures
Not Eligible

You will not qualify if you...

  • Any social or medical condition that study staff believe would make participation unsafe or complicate data interpretation
  • Physical, psychological, or social conditions that may make participation unsuitable as noted by study staff

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 3 years

Participants are visited every three months for up to three years to review medical records, undergo brief physical exams, urine pregnancy tests, answer survey questions, and self-collect vaginal swabs for future testing.

Quarterly visits for up to 3 years

Trial Site Locations

Total: 1 location

1

University of Zambia

Lusaka, Zambia

Actively Recruiting

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Research Team

M

Mutale Sampa

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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